The story shifts back to Gabriel coming back to consciousness...
Lexine: "Hi there. I finally found some painkillers. They should work pretty fast."
Weller: "You're not kidding. The cannon's stopped... Where's McNeill?"
Lexine: "He said he was on his way back. That was a while ago, though."
Weller: "Give him a call. We should be ready to go when he arrives."
Lexine: "Nate? Nate? This is Lexine. Nate? Come in! McNeill? Oh god, he's not..."
Weller: "No, keep trying."
Lexine: "Nate, where are you? Nate, come in!"
Frustrated, she whips the radio at the wall.
Weller: "Lexine? What the hell?"
Lexine: "That's it! We're getting out of here! Nate, Dr. Howell, Nicole... I won't let them have died for nothing!" (Well Nicole died for nothing actually.)
The groans of necromorphs can be heard...
Weller: "Shit!"
Lexine: "Move! Into the shuttle!"

Slashers and a Stinger come into the booth. In Free Look Mode, there's a Ripper Upgrade in the vent above you. There's a Text Log on the other side of the desk. Outside the control room, more Slashers and Stingers attack. I'd like to take this moment to point out that there isn't much Ammo to be found (there's a few boxes around) on this level, so don't be wasteful.

Lexine: "Weller, behind you!"
Weller: "Run!"

Keep blasting those Stingers and Slashers. A whole bunch of necromorphs come charging in, but you run away.

Weller: "Lexine, watch my back! Jesus!"
Lexine: "Hurry!"
Weller: "The control panel, hit it!"

You climb onto the rising platform. There's 2 boxes on it. A Stinger climbs up the wall to reach you and a Slasher busts through the vent.

Lexine: "That won't stop them for very long."
Weller: "C'mon."

Slashers, Stingers, Exploders, and Pregnants will all get in your way. There's an explosive barrel here. You can also pick up and throw the debris here, though their effectiveness is low. As you move, you look to the left, where a Contact Beam Upgrade is.

Lexine: "How are you holding up?"
Weller: "I'll be all right. Keep moving!"

There's an Audio Log to the left here. You'll face a couple Slashers, Stingers, and a Pregnant as you move around, and find a Force Gun Upgrade in plain sight. However, 3 Airbornes attack you at once.

Lexine: "Weller, you deal with them! I'll prepare the ship!"
Weller: "I didn't know you could fly!"
Lexine: "I can't. But I can figure out how to fire an engine, and you're a better shot than me!"
Weller: "Where the hell are you, McNeill?"

Mostly Stingers and Slashers, with a couple Exploders appearing towards the end.

Weller: "They're still coming! How are you doing?"
Lexine: "Getting there! Just hold them off! And keep a lookout for McNeill!"

Inside the shuttle is a Medium Health (if you didn't grab it earlier) and Contact Beam. Outside the shuttle are more even more Slashers and Stingers.

Weller: "They're still coming!"
Lexine: "Hang on, test-firing the thrusters now!"

Now you get mobbed by Slashers, Stingers, Exploders, and Pregnants.

Weller: "Lexine, we have to go!"
Lexine: "But Nate..."
Weller: "He's gone! And if we don't leave right away, so are we!"

Just Slashers and a couple Pregnants now. Loud booms are heard...

Lexine: "What was that?"
Weller: "A contact beam! Shit, if one of those crazies has got their hands on firepower like that... McNeill!"
Despite his injury, Nate is able to fight his way through to the shuttle.
Lexine: "Nate!"
Weller: "Shit, your hand..."
McNeill: "I'll be fine! Just close the goddamn door!"
Several creatures approach the door, but it closes before they can get in. (You are free to shoot them though.)
Lexine: "Oh my god... Nate..."
McNeill: "Later, right now we need to leave. Move over. Hold onto something!"
Nate manages to take the ship out of the dock and into space.
Lexine: "It's over! We made it!"
McNeill: "Yeah, we did. Here, take over. We're on course for the Sprawl; you just need to monitor the autopilot."
Weller: "There'll be a medkit in the galley."
McNeill: "I'm all right. It can wait 'till we get home." (HE'S HARDCORE!)
Weller: "Never thought I'd be so happy about seeing the Sprawl... Who'd have guessed we had one last mission in us?"
McNeill: "Not just "one" last mission... The last. As of now, I am officially retired."
Weller: "Hahaha... All right, wake me up when we reach the Sprawl..."
Radio: "U.S.G. Ishimura... This is the emergency maintenance team of the USG Kellion responding to your distress call. Come in, Ishimura..."
Lexine: "Hey! This is Ishimura Shuttle 23! Kellion, don't go in there! Do you hear me? Dammit! Respond! Come in Kellion! This is Ishimura Shuttle 23! I am warning you... This is a warning... Do not go in there!"

Afterwards, there is a bunch of images that suggest something happens, but we don't know because it is a vague ending.
???: "It's calling to us... Don't you see? Death is not the end... Now, maybe you'll understand..."